Searchable abstracts of presentations at key conferences in endocrinology

ea0037ep855 | Thyroid cancer | ECE2015

Vitamin-D neutralising CYP24A1 gene expression in thyroid fine-needle aspiration biopsy samples

Balla Bernadett , Horvath Peter , Tobias Balint , Gyori Gabriella , Jaray Balazs , Kosa Janos , Lakatos Peter

Objectives: We previously published the result of CYP24A1 gene expression in one hundred, solely papillary thyroid carcinoma (PTC) compared to its own tumour free control from the same patient. We report an increase in CYP24A1 gene transcription in more than half of analysed PTCs. Elevated CYP24A1 protein expression was also observed in the cancerous tissue section compared to peritumoural normal thyroid tissue. In the present study we aimed to examine CYP24A1 gene transcripti...